All destinations from Mainz
Mainz → Prague
1 direct departure on Mon, November 23, 2026Direct, no changes
Plan the journey
Timetable runs to March 27, 2027
Next dates
Your trip
Departure
16:20
Mainz
Mainz central train station (exit West)
8 h 10 minDirect, no changes
Arrival
00:30+1 day
Prague
11/24
- Operator
- FlixBus
- Runs
- Line
- Medyka - Frankfurt - the Hague
kavolu sells no tickets. The link opens the route page at FlixBus — the price and the seats are shown there.
Nothing else runs on this route that day.
Mainz → Prague at a glance
Direct coaches from Mainz to Prague run once daily. The ride takes 8 h 10 min. It always leaves at 16:20. Nothing leaves on this route between 10 pm and 6 am. In Mainz, it leaves from the stop “Mainz central train station (exit West)”. All rides are run by FlixBus. Direct coaches back from Prague to Mainz run 2× daily.