All destinations from Siena
Siena → Rome
10 direct departures on Wed, November 25, 2026Direct, no changes
Plan the journey
Timetable runs to March 27, 2027
Next dates
Your trip
Departure
06:50
Siena
Siena (piazza Gramsci)
3 h 5 minDirect, no changes
Arrival
09:55
Rome
- Operator
- FlixBus
- Runs
- Line
- Rom FCO ✈ - Siena - Poggibonsi
kavolu sells no tickets. The link opens the route page at FlixBus — the price and the seats are shown there.
Other departures on Wed, November 25, 2026
Siena → Rome at a glance
Direct coaches from Siena to Rome run approx. 15× daily. The ride takes between 2 h 40 min and 3 h 5 min. The earliest departure is at 05:35, the latest at 22:25. 13 of the 103 weekly departures are between 10 pm and 6 am. In Siena, it leaves from 3 stops, most often from “Siena (Stazione FS)”. All rides are run by FlixBus. Direct coaches back from Rome to Siena run approx. 14× daily.